Most of Osbourne lies to the West of US 281 which meets US 24 in the Northern part of town.

The Geodetic Center has a a replica of the geodetic marker of North America, located 18 miles south of Osborne, is in Roadside park. You can also find information about the Geodetic Marker of North America in the center. The actual marker is on the National Register of Historic Places and is on pastureland originally homesteaded around 1885. The Osborne County Historical museum, which has horse-drawn farm machinery, stone mason’s tools, medical equipment, kitchenware and farm tools on display is located in this city and the Osbourne Municipal airport, with two runways running approximately 4000 feet long and 2900 feet long is just East of the city .